In a 1998 Sesame Street episode, the agency recruits Slimey for a mission to the moon.  Staffed by a training officer & several highly trained worm technicians, they oversee the testing of a team of brave astronauts.
The roster includes Spaghettini from Italy, Squishta from Romania, Legusano from Colombia, Squashimi from Japan, Slogoshki from Poland, other worms from Puerto Rico & Zambia, & Selma Worm, who is actually a chicken dressed as a worm.
Five worms are ultimately chosen as the crew of the Wiggleprise. Their mission is administered from a control center based on Sesame Street, led by Professor Albert Einslime. It is this same crew of worms that can be seen in the recurring Worms in Space sketches.
Einslime & WASA returned to Sesame Street in 2007 to launch Slimey's girlfriend Glo Worm into space.  As before, worm technology couldn't sufficiently launch the rocket without some help from a Muppet; in this case the number 0, who saved the day by standing in for the final number of the count down.